Complex regional pain syndrome (CRPS), formerly known as reflex sympathetic dystrophy (RSD) was first described 150 years ago as a burning pain with observable trophic skin changes (Maihofner). CRPS is characterized by inflammation, autonomic dysfunction, and neurological changes within the CNS (Maihofner).
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- Image from: http://trialx.com/curebyte/2011/07/11/photos-related-to-complex-regional-pain-syndrome-type-ii/